Team : Factors of persistence of leukemic cells

The team “Factors of persistence of leukemic cells” focused on the discovery of factors that contribute to the long-term persistence of leukemic cells such as tumor dormancy, and to the characterization of genomic markers predictive of the evolution of hematological malignancies.

The team is located in Institut pour la Recherche sur le Cancer de Lille www.ircl.org for its cell biology and in hematology laboratory and high throughput genomic technologies for CHU de Lille (Lille Academic Hospital) for its tumor cell bank and translational molecular biology activities. The team shares the same building with Flow cytometry and Cell sorting platforms and several team members are involved in both activities.

The team is historically linked with the Department of Clinical Hematology (Service des Maladies du Sang, CHU), the Laboratory of Hematology, and the Department of cytogenetic form the nearby academic hospital. Several team members are primary affiliated to the CHU, and research projects are directly issued from this high degree of integration.